Basic information and current topics regarding Flaviviridae

Directions in Research

This page contains a review of the reviews.
If you are looking for the full reviews, please look in the Current Research Summaries section.

There’s a lot of ongoing research regarding Flaviviruses–as they represent a large portion of medically important viruses. Current research seems to be dedicated to a further understanding of how Flaviviruses work, what symptoms they cause, and how they cause those symptoms.

An article on the transcriptopmic profile of Japanese Encephalitis reaches into the depths of the host organism during the early and late phases of infection. To see a list of research articles, look here. The directions of current research are vast and seemingly endless. Despite which direction any research heads, they all collaborate towards a common effort: the completed, finalized understanding of a virus that has plagued humankind for centuries. No matter how ‘niche’ an article may seem, they all surface as vital elements in this larger puzzle.

The burden of understanding has been laid upon the student, and it is, without doubt, a responsibility which may not be taken lightly. Human lives are at the heart of every article, every theory, and constantly on the mind of every researcher working diligently towards the refinement of this knowledge. They are contributing to the building of a structure which will one day represent the riddance of outbreaks and deaths caused by this family of viruses. And, with an understanding of this structure, we are allowed to place our supports–our contribution. I believe Emerson put it quite clearly when speaking of love:

…The soul of man, embodied here on earth, went roaming up and down in quest of that other world of its own, out of which it came into this, but was soon stupefied by the light of the natural sun, and unable to see any other objects than those of this world, which are but shadows of real things … because it suggests to him the presence of that which indeed is within the beauty, and the cause of the beauty.2

It is not the understanding nor the glory of proof that drives us to study viruses. Instead, it is the simple love for our own kind and its persistence which drives us to write such ‘niche’ articles and study such a complicated science. While continuing on your chosen path of academia, don’t forget that those who set those paths for you, those who wrote such mundane and impersonal articles, overflowing with graphs, write each word and set every curriculum with the hopes that someone who was influenced by their work will persevere to create an even greater future for us all–that their passion will persist throughout time. Emerson ends his essay on this same idea:

Thus are we put in training for a love which knows not sex, nor person, nor partiality, but which seeks virtue and wisdom everywhere, to the end of increasing virtue and wisdom. We are by nature observers, and thereby learners. That is our permanent state.2


1. Nimesh Gupta and P v Lakshmana Rao. (2011).Transcriptomic profile of host response in Japanese encephalitis virus infection. Virology Journal 2011, 8:92 doi:10.1186/1743-422X-8-92

2. Ralph Waldo Emerson. (1844). The Prose Works of Ralph Waldo Emerson. 1st ed. Ticknor & Fields. Osgood, Boston