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Basic information and current topics regarding Flaviviridae
Viruses belonging to the family Flaviviridae are considered class 4 viruses within the Baltimore classification scheme. Viruses in this class are positive sense, single stranded RNA viruses which replicate their genome through a partially double-stranded intermediate form.
The following sections address the life-cycle of Flaviviridae specifically, but they still fall close to the generic category of class 4 viruses. The life-cycle has been divided into several pages for your convenience:
Virus attachment, entry, and uncoating — This section overviews the proteins important to a flavivirus’ tissue tropism, the method used for entering the cell, and the strategies used for signaling viral uncoating.
Expression and biosynthesis — Here we discuss the various genes of the generic flavivirus genome and the timing related to each gene. This section overlaps with the following section’s time-line, as viral assembly and genome expression patterns are topics which happen synchronously.
Virus assembly — This page delves into the structure of Flaviviridae and how that structure is created.
Virus exit strategies — A short but conclusive section briefly describing how the Flaviviridae family leaves its host.
picture source: http://www.pnas.org/content/99/18/11555.long